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Image Search Results
Journal: Journal of Circulating Biomarkers
Article Title: Quantification of Cell-Free HER-2 DNA in Plasma from Breast Cancer Patients: Sensitivity for Detection of Metastatic Recurrence and Gene Amplification
doi: 10.5772/61320
Figure Lengend Snippet: In gel: HER-2 gene PCR product corresponding to 76 bp and B2M gene PCR product corresponding to 102 bp
Article Snippet: IHC was analysed using the Hercep Test (DakoCytomation, Glostrup, Denmark) and FISH was analysed with the
Techniques:
Journal: Journal of Circulating Biomarkers
Article Title: Quantification of Cell-Free HER-2 DNA in Plasma from Breast Cancer Patients: Sensitivity for Detection of Metastatic Recurrence and Gene Amplification
doi: 10.5772/61320
Figure Lengend Snippet: (a) Preoperative plasma cfHER-2 DNA and cfB2M DNA levels from tissue HER-2-positive patients compared with levels from healthy controls. (b) Preoperative plasma cfHER-2 DNA and cfB2M DNA from tissue HER-2-negative patients compared with levels from healthy controls.
Article Snippet: IHC was analysed using the Hercep Test (DakoCytomation, Glostrup, Denmark) and FISH was analysed with the
Techniques:
Journal: Journal of Circulating Biomarkers
Article Title: Quantification of Cell-Free HER-2 DNA in Plasma from Breast Cancer Patients: Sensitivity for Detection of Metastatic Recurrence and Gene Amplification
doi: 10.5772/61320
Figure Lengend Snippet: Ratio levels of cfHER-2 DNA/cfB2M DNA in tissue HER-2-negative patients (n=454) compared to tissue HER-2-positive patients (n=590)
Article Snippet: IHC was analysed using the Hercep Test (DakoCytomation, Glostrup, Denmark) and FISH was analysed with the
Techniques:
Journal: Journal of Clinical Medicine
Article Title: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry
doi: 10.3390/jcm9040935
Figure Lengend Snippet: Baseline characteristics according to central HER2 status.
Article Snippet: In the local laboratories, the HercepTest (Dako, Glostrup, Denmark), HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody, PATHWAY, Roche (Ventana) and LDT c-erbB-2 Oncoprotein (HER-2), clone CB11 (Dako Autostainer Plus, Glostrup, Denmark) were used for IHC analysis, and ISH analysis was performed by using the PathVysion HER-2 DNA Probe Kit (Abbott, Des Plaines, USA), HER-2 Dual ISH DNA Probe Cocktail Assay, Roche (Ventana, Oro Valley, USA) or
Techniques:
Journal: Journal of Clinical Medicine
Article Title: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry
doi: 10.3390/jcm9040935
Figure Lengend Snippet: HER2 concordance/discordance rate according to local/central testing.
Article Snippet: In the local laboratories, the HercepTest (Dako, Glostrup, Denmark), HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody, PATHWAY, Roche (Ventana) and LDT c-erbB-2 Oncoprotein (HER-2), clone CB11 (Dako Autostainer Plus, Glostrup, Denmark) were used for IHC analysis, and ISH analysis was performed by using the PathVysion HER-2 DNA Probe Kit (Abbott, Des Plaines, USA), HER-2 Dual ISH DNA Probe Cocktail Assay, Roche (Ventana, Oro Valley, USA) or
Techniques:
Journal: Journal of Clinical Medicine
Article Title: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry
doi: 10.3390/jcm9040935
Figure Lengend Snippet: HER2 discordance rate according to local HER2 testing year. Blue line: cumulative HER2 tests, red line: cumulative discordant HER2 results.
Article Snippet: In the local laboratories, the HercepTest (Dako, Glostrup, Denmark), HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody, PATHWAY, Roche (Ventana) and LDT c-erbB-2 Oncoprotein (HER-2), clone CB11 (Dako Autostainer Plus, Glostrup, Denmark) were used for IHC analysis, and ISH analysis was performed by using the PathVysion HER-2 DNA Probe Kit (Abbott, Des Plaines, USA), HER-2 Dual ISH DNA Probe Cocktail Assay, Roche (Ventana, Oro Valley, USA) or
Techniques:
Journal: Journal of Clinical Medicine
Article Title: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry
doi: 10.3390/jcm9040935
Figure Lengend Snippet: Comparison of local and central HER2 IHC result and impact on HER2 status.
Article Snippet: In the local laboratories, the HercepTest (Dako, Glostrup, Denmark), HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody, PATHWAY, Roche (Ventana) and LDT c-erbB-2 Oncoprotein (HER-2), clone CB11 (Dako Autostainer Plus, Glostrup, Denmark) were used for IHC analysis, and ISH analysis was performed by using the PathVysion HER-2 DNA Probe Kit (Abbott, Des Plaines, USA), HER-2 Dual ISH DNA Probe Cocktail Assay, Roche (Ventana, Oro Valley, USA) or
Techniques: Immunohistochemistry
Journal: Journal of Clinical Medicine
Article Title: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry
doi: 10.3390/jcm9040935
Figure Lengend Snippet: Progression-free survival ( a ) and overall survival ( b ) with palliative first-line trastuzumab based systemic therapy in centrally HER2 positive advanced gastric/GEJ cancer patients. The tick marks on the curves represents censored patients.
Article Snippet: In the local laboratories, the HercepTest (Dako, Glostrup, Denmark), HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody, PATHWAY, Roche (Ventana) and LDT c-erbB-2 Oncoprotein (HER-2), clone CB11 (Dako Autostainer Plus, Glostrup, Denmark) were used for IHC analysis, and ISH analysis was performed by using the PathVysion HER-2 DNA Probe Kit (Abbott, Des Plaines, USA), HER-2 Dual ISH DNA Probe Cocktail Assay, Roche (Ventana, Oro Valley, USA) or
Techniques:
Journal: Journal of Clinical Medicine
Article Title: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer—Results from the AGMT GASTRIC-5 Registry
doi: 10.3390/jcm9040935
Figure Lengend Snippet: Overall survival from diagnosis of metastatic gastric/GEJ cancer according to central HER2 status and according to trastuzumab front-line treatment status. The tick marks on the curves represents censored patients. * According to standard of care.
Article Snippet: In the local laboratories, the HercepTest (Dako, Glostrup, Denmark), HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody, PATHWAY, Roche (Ventana) and LDT c-erbB-2 Oncoprotein (HER-2), clone CB11 (Dako Autostainer Plus, Glostrup, Denmark) were used for IHC analysis, and ISH analysis was performed by using the PathVysion HER-2 DNA Probe Kit (Abbott, Des Plaines, USA), HER-2 Dual ISH DNA Probe Cocktail Assay, Roche (Ventana, Oro Valley, USA) or
Techniques:
Journal: British Journal of Cancer
Article Title: Diffuse EGFR staining is associated with reduced overall survival in locally advanced oesophageal squamous cell cancer
doi: 10.1038/sj.bjc.6602625
Figure Lengend Snippet: Immunohistochemical expression of carcinogenesis factors in SCCO: ( A ) p53 intense nuclear staining, HESx100, ( B ) EGFR intense membranous staining, HES × 200, ( C ) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; ( D ) HER-2 complete and strong membranous staining, scored ‘3+’, HES × 400; ( E ) CD117 focal cytoplasmic staining, HES × 200.
Article Snippet: Then, sections were rinsed with phosphate-buffered saline (PBS) and incubated with selected primary antibodies as follows: (i) a polyclonal antibody from rabbit (Santa Cruz Biotech®, 1/100 dilution and 45-min incubation) for VEGF; (ii)
Techniques: Immunohistochemical staining, Expressing, Staining